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Results

162,977

Enrollees in Nigeria, Kenya and Tanzania


16,184,200

Total disbursed loan amount in USD


1,938,199


Number of patient visits to SafeCare facilities per month


1,954

Number of active clinics in the SafeCare program

Publications

Emerging HIV-1 drug resistance after roll-out of antiretroviral therapy in sub-Saharan Africa

Jan 1, 2013


This review provides an update of recent data on the development of HIV-1 drug resistance during treatment and its transmission in sub-Saharan Africa after the scale-up of antiretroviral therapy (ART).

Recent findings: Evidence is accumulating of a rising prevalence of transmitted HIV drug resistance (TDR), predominantly associated with nonnucleoside reverse transcriptase inhibitors (NNRTIs), in east and southern Africa. Pretherapy resistance is associated with first-line therapy failure. Accumulation of resistance mutations during first-line failure can be prevented by early detection and timely switching to second-line ART. Important gaps in service delivery and programme performance, associated with resistance development, affect a considerable proportion of ART programmes, particularly with respect to inadequate supply systems and patient retention. The reduction in new HIV infections associated with earlier use of ART is predicted to outweigh the risk of increasing TDR. Future levels of TDR are estimated to be diminished by improving switching practices to second-line regimens.

Summary: TDR is on the rise after the recent scale-up of ART in Africa. To prevent the development and spread of drug resistance and sustain the effectiveness of ART programmes, there is a need to improve drug supply systems, patient retention and access to routine viral load monitoring. Enhanced resistance monitoring is warranted in Africa.

 Click here to read the full article.

 

 

Author: Hamers, R.L., Sigaloff, K.C.E., Kityo, C., Mugyenyi, P. and Rinke de Wit, T.F.

Date: January 2013

News

On 12 September 2016, OPIC, Calvert Foundation and two private investors announce expansion
PharmAccess and its German consultancy partner GFA have won a 27.3 million Euros tender from the German development bank KfW to improve access to healthcare for low-income pregnant women in 5 regions of Tanzania.
President Felipe Nyuse of Mozambique officially opened the University Clinic

Publications

A population-based study
Date: September, 2015

Research findings on Health Insurance Fund supported programs

Date: February, 2015